'#Employment and #Energy' - a #Research article in the Journal of Ecological Society on #ScienceOpen:
https://www.scienceopen.com/hosted-document?doi=10.54081/JES.028/07
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'Assessing technical and scale efficiencies in tilapia production: influential factors and insights' - an article in the @EDPSciences UN #SDGs #Research collection on #ScienceOpen:
https://www.scienceopen.com/document?vid=706c5491-5db0-4c39-bca8-a7f97f74efa4
ScienceOpenAssessing technical and scale efficiencies in tilapia production: influential factors and insights<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d4716334e75">This study assessed the technical and scale efficiency of tilapia farmers in Bangladesh
with a focus on identifying key factors influencing their efficiency levels. Data
from 199 randomly selected tilapia farmers were analyzed using Data Envelopment Analysis
(DEA), followed by a Tobit regression model to determine the key variables affecting
efficiency. The results revealed a mean TE of 0.77 under CRS, 0.83 under VRS, and
a mean SE of 0.92, indicating that most inefficiencies were technical rather than
scale-related issues. The study also identified farming training, credit access, and
years of experience had a positive effect on TE, while adverse climatic conditions
negatively impacted efficiency. The findings emphasize the importance of mitigating
climate impacts and improving resource management to enhance efficiency. Expanding
credit access, improving training programs, and taking initiatives for mitigating
climate impacts could significantly improve the efficiency and long-term viability
of tilapia production in the region.
</p>
'Regulatory and policy analysis of employment and health protections in Indonesia’s creative economy' - an article in the @EDPSciences UN #SDGs #Research collection on #ScienceOpen:
https://www.scienceopen.com/document?vid=f4e86a8b-edb4-486a-816d-c6d863962594
ScienceOpenRegulatory and policy analysis of employment and health protections in Indonesia’s creative economy<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1238569e108">This research explores the growing role of the creative economy and the regulatory
gaps that impact labor protection, specifically in the creative industry sector. The
digital transformation of the creative sector has led to significant economic contributions
but also challenges regarding labor protection, especially health security for workers.
Despite advancements, such as the introduction of social health insurance in Vietnam,
Indonesia faces regulatory shortcomings in providing adequate health protection for
creative workers, many of whom are freelancers or contract workers. Using a normative
legal research method, this study analyzes key legal frameworks, including laws related
to manpower, social security, and creative economy regulations, to assess the extent
to which existing policies address labor and health protection in the digital era.
The research highlights critical gaps in health coverage for workers with less than
six months of employment and suggests that expanding social security coverage, increasing
legal literacy, and enacting targeted regulatory reforms are essential for creating
a more inclusive and sustainable creative economy workforce. The study also draws
lessons from Vietnam’s successful implementation of Social Health Insurance. By addressing
these regulatory shortcomings, Indonesia can better ensure the welfare of creative
workers and enhance their contributions to the national economy.
</p>
'Growth and yield performance of drought-stressed soybean ( Glycine max L.) treated with neem-mediated silver nanoparticles' - an article in the @EDPSciences UN #SDGs #Research collection on #ScienceOpen:
https://www.scienceopen.com/document?vid=be176bb6-5a57-452e-9649-a1873e0cbdcc
ScienceOpenGrowth and yield performance of drought-stressed soybean ( <i>Glycine max</i> L.) treated with neem-mediated silver nanoparticles<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d9219553e162">The utilization of nanotechnology in agriculture has demonstrated significant potential,
particularly in enhancing crop resilience to environmental stress. This study investigated
the effect of silver nanoparticles (AgNPs) in seed treatment on soybean performance
under drought conditions. The study used a factorial CRD with four replicates. The
experimental factors included seed treatments (control, AgNP priming, and AgNP coating)
and drought stress levels represented by the field water capacity (FWC) of 80%, 60%,
and 40%. The results demonstrated that seed treatment with AgNPs significantly increased
plant growth in AgNP coatings based on plant height but did not significantly increase
all soybean yield variables. FWC of 40-60% showed severe and moderate stress effects
on soybean, which significantly decreased the leaf number but increased the leaf green
index. In conclusion, AgNP seed treatment had a limited effect on soybean production
but could be a potential approach to enhance drought tolerance.
</p>
'Genotype-environment interaction and yield stability of five Vigna radiata genotypes under contrasting agrivoltaics environments in a tropical dry season climate' - a #Research article in 'CABI #Agriculture and #Bioscience' on #ScienceOpen:
https://www.scienceopen.com/document?vid=860657f9-c3aa-483b-a835-9145909a6b6b
'Fall armyworm outbreak in mainland Southeast Asia: Spatial mapping and impact on regional maize production' - a #Research article in 'CABI #Agriculture and #Bioscience' on #ScienceOpen:
https://www.scienceopen.com/document?vid=b42921f4-20d7-4248-9597-63a07bedafed
'Effects of host switching and successive multigenerational rearing of the parasitoid Eretmocerus corni (Hymenoptera: Aphelinidae) on host preference and adaptation' - a #Research article in 'CABI #Agriculture and #Bioscience' on #ScienceOpen:
https://www.scienceopen.com/document?vid=ab8d2640-a752-4767-8d49-f255ccf93360
ScienceOpenEffects of host switching and successive multigenerational rearing of the parasitoid <i>Eretmocerus corni</i> (Hymenoptera: Aphelinidae) on host preference and adaptation<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="P000003">Background: The adaptive strategies of parasitoids against different hosts may evolve
under successive multigenerational rearing in alternative hosts; therefore, it is
crucial to validate the maintenance and optimization of parasitoid adaptations to
target pests during mass rearing.
<i>Eretmocerus corni</i> Haldeman (Hymenoptera: Aphelinidae) is a biological control agent for managing whitefly
pests. Here, we investigated the effects on preference and adaptation of adult
<i>E. corni</i> transferred from its original host,
<i>Trialeurodes vaporariorum</i> Westwood (Hemiptera: Aleyrodidae), to a new host,
<i>Bemisia tabaci</i> Gennadius (Hemiptera: Aleyrodidae), through successive multigenerational rearing
on
<i>B. tabaci</i> nymphs. Results: The results of the choice assays showed that for the first five
generations, the parasitoids showed a clear preference for the original rearing host
<i>T. vaporariorum</i> nymphs. However, after 15 generations of rearing on
<i>B. tabaci</i> nymphs, there was a preference for
<i>B. tabaci</i> nymphs compared to
<i>T. vaporariorum</i> nymphs. No-choice assays showed that there was no significant increase in the number
of
<i>B. tabaci</i> nymphs parasitized and total mortality in all generations, but the number of
<i>T. vaporariorum</i> nymphs parasitized and total mortality were both significantly higher in the control
than the10th and 15th generations. When
<i>E. corni</i> parasitized
<i>T. vaporariorum</i> nymphs, the developmental time of the 1st generation offspring was significantly
shorter than that of other generations. Host feeding, offspring female ratio and emergence
rate did not differ among generations or between host species. Conclusion: Our analyses
showed that successive rearing of
<i>E. corni</i> on an alternative host was able to enhance the preference for that host. However,
despite this increase in preference, the developmental suitability did not change
significantly among generations. This study provides fundamental information for understanding
the parasitism performance of
<i>E. corni</i> across different whitefly hosts over multiple generations.
</p>
'No effect of transgenic St-Prrn-ACT potatoes on Arma chinensis, a natural enemy of the Colorado potato beetle' - a #Research article in 'CABI #Agriculture and #Bioscience' on #ScienceOpen:
https://www.scienceopen.com/document?vid=296fbaf4-c5c0-47de-87a8-78fdae5a01d3
ScienceOpenNo effect of transgenic <i>St</i>-Prrn-ACT potatoes on <i>Arma chinensis</i>, a natural enemy of the Colorado potato beetle<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="P000002">Potato stands as an important vegetable crop globally. The Colorado potato beetle
(CPB) emerges as a pervasive quarantine pest with a worldwide footprint, inflicting
devastating consequences on potato crops.
<i>Arma chinensis</i> (Fallou) is an important predator of several agricultural and forestry pests, including
the CPB. Previous investigations have demonstrated the potent induction of RNAi responses
in beetles through the transgenic manipulation of potato plants targeting the β-Actin
(ACT) gene. By expressing double-stranded RNA (dsRNA) in potato plastids, specifically
targeting the β-Actin (ACT) gene of the CPB, transplastomic potato plants can trigger
the beetle’s RNA interference response to kill the CPB. Our study evaluates the effect
of transgenic
<i>St</i>-Prrn-ACT potatoes on
<i>A. chinensis</i>. Furthermore, through the tertiary nutritional relationship test of the different
potato varieties-CPB-
<i>A. chinensis</i>, we aim to understand whether the transgenic
<i>St</i>-Prrn-ACT potato can affect the
<i>A. chinensis</i>. To discern this, wild-type
<i>St</i>-wt and economically significant cultivar Holland 15 were judiciously chosen as controls
for comparison against the transgenic
<i>St</i>-Prrn-ACT. Comparison of survival curves, predation volume, mean weight, as well as
the activities of detoxification enzymes and protective enzymes in the different potatoes
was made for CPB and
<i>A. chinensis</i>. The study revealed an absence of statistically significant variances in survival
rates, detoxification enzyme activities, and protective enzyme activities among different
specimens when pitted against the
<i>A. chinensis</i>. The study also revealed no effect of transgenic
<i>St</i>-Prrn-ACT potatoes on
<i>A. chinensis</i>, following exposure through the CPB.
</p>
'Two-group bubble size distribution evolution in vertical two-phase flow: Mechanistic model development and evaluation in a tight-lattice rod bundle' - a 'National Science Open' article published by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=dac3b468-6270-4ed7-bdff-41a4f3a6922c
'Revealing unipolar thermoelectric performance in bipolar polymer' - a 'National Science Open' article published by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=b75c891a-823a-4452-aa26-963f808ea58a
'Self-confined electrohydrodynamic printing on micro-structured substrate for flexible transparent electrodes with embedded metal mesh' - a 'National Science Open' article published by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=affa0830-e7d5-4f52-94d0-05b18431d0c0
'Epidemiological changes in Toxoplasma infection: a 7-year longitudinal study in pregnant women in Lyon, France, 2017–2023
Translated title: Évolution épidémiologique de l’infection à Toxoplasma : étude longitudinale sur 7 ans chez les femmes enceintes à Lyon (2017-2023)'
- an article in 'Parasite' by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=0024b3de-afb9-43b1-a6a8-285bffcc8003
'Culturable bacteria and fungi in Ixodes, Dermacentor, Amblyomma and Ornithodoros ticks
Translated title: Bactéries et champignons cultivables chez les tiques Ixodes, Dermacentor, Amblyomma et Ornithodoros' - an article in 'Parasite' by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=281df285-4c19-4999-97c0-df2d0abf57c5
ScienceOpenCulturable bacteria and fungi in <i>Ixodes</i>, <i>Dermacentor</i>, <i>Amblyomma</i> and <i>Ornithodoros</i> ticks <span class="so-article-trans-title" dir="auto"> Translated title: Bactéries et champignons cultivables chez les tiques <i>Ixodes</i>, <i>Dermacentor</i>, <i>Amblyomma</i> et <i>Ornithodoros</i> </span><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d19498493e208">Ticks are ectoparasites harboring complex microbial communities, typically dominated
by nutritional symbionts that produce B vitamins and sometimes including pathogens
affecting human and animal health. However, ticks also host a variety of commensal
microbes whose diversity remains poorly documented. In this study, we isolated and
identified culturable bacteria and fungi associated with various tick species from
the genera
<i>Ixodes</i>,
<i>Dermacentor</i>,
<i>Amblyomma</i>, and
<i>Ornithodoros</i>, collected from their natural habitats or hosts in France and French Guiana. A total
of 111 bacterial and 27 fungal isolates were obtained which were then identified using
both molecular and morphological approaches. Substantial fungal diversity was observed
in a few ticks, whereas culturable bacteria displayed a broader distribution and diversity
across tick species. Interestingly, the diversity of culturable bacteria and fungi
revealed a microbiome structure that reflected the ecological niches of the tick host,
indicating habitat-specific microbial associations and a potential ecological role
in tick biology. The isolation of common gut bacteria of other arthropods, as well
as the isolation of a viable entomopathogenic fungus, underscores the potential influence
of these microbes on tick biology.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d19498493e223">Les tiques sont des ectoparasites abritant des communautés microbiennes complexes,
généralement dominées par des symbiotes nutritionnels qui produisent des vitamines
B et parfois incluant des pathogènes affectant la santé humaine et animale. Cependant,
les tiques hébergent également une variété de microbes commensaux dont la diversité
reste mal documentée. Dans cette étude, nous avons isolé et identifié des bactéries
et champignons cultivables associés à diverses espèces de tiques des genres
<i>Ixodes</i>,
<i>Dermacentor</i>,
<i>Amblyomma</i> et
<i>Ornithodoros</i>, collectées dans leurs habitats naturels ou hôtes en France et en Guyane française.
Au total, 111 isolats bactériens et 27 isolats fongiques ont été obtenus, qui ont
ensuite été identifiés à l’aide d’approches moléculaires et morphologiques. Une diversité
fongique substantielle a été observée chez quelques tiques, tandis que les bactéries
cultivables présentaient une distribution et une diversité plus larges parmi les espèces
de tiques. Il est intéressant de noter que la diversité des bactéries et des champignons
cultivables a révélé une structure du microbiome qui reflétait les niches écologiques
de l’hôte tique, indiquant des associations microbiennes spécifiques à l’habitat et
un rôle écologique potentiel dans la biologie des tiques. L’isolement de bactéries
intestinales communes d’autres arthropodes, ainsi que l’isolement d’un champignon
entomopathogène viable, soulignent l’influence potentielle de ces microbes sur la
biologie des tiques.
</p>
'Rotating-platform deep-dish total knee arthroplasty with restricted kinematic alignment: Five-year clinical and functional outcomes' - an article in SICOT-J by @EDPSciences on #ScienceOpen:
https://www.scienceopen.com/document?vid=ed601e88-077c-490c-bf68-f2b78ac3e313
ScienceOpenRotating-platform deep-dish total knee arthroplasty with restricted kinematic alignment: Five-year clinical and functional outcomes<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d6221308e185">
<i>Introduction</i>: Total knee arthroplasty (TKA) utilizing deep-dish tibial inserts has gained interest
due to its high congruency and enhanced stability. However, due to the advent of more
personalized alignment philosophies, the combination of a rotating-platform deep-dish
TKA design with restricted kinematic alignment (rKA) might improve patient satisfaction.
Therefore, this study evaluated the five-year clinical and functional outcomes of
rKA with a deep-dish TKA design.
<i>Methods</i>: A retrospective analysis was conducted on patients who underwent primary TKA with
a rotating-platform deep-dish design and rKA. Of 143 eligible patients, 123 completed
five-year follow-up. Clinical and radiographic assessments included the five-year
postoperative results: Knee Society Score (KSS), patient satisfaction, range of motion,
coronal limb and implant alignment, postoperative complications and implant survivorship.
Statistical analyses compared preoperative and postoperative outcomes with paired
analyses.
<i>Results</i>: Median KSS Knee and Function scores significantly improved from 70 (IQR 5) and 60
(IQR 26) preoperatively to 90 (IQR 20) and 93 (IQR 21) postoperatively (
<i>p</i> < 0.001). Postoperative coronal alignment in this study encompassed a hip-knee-ankle
angle was 178.1° ± 3.5, a Lateral Distal Femoral Angle of 89.9° ± 2.6, and a Medial
Proximal Tibial Angle of 88.6° ± 2.2. At five years, 94% of patients were either satisfied
or very satisfied. The revision-free survival rate was 98%. Periprosthetic joint infection
and arthrofibrosis were the most common complications (1.6% for both groups separately),
followed by aseptic loosening of a cementless femoral component (0.8%) and patellar
dislocation (0.8%).
<i>Discussion</i>: Rotating-platform deep-dish TKA with restricted kinematic alignment results in excellent
functional outcomes, high patient satisfaction, and low complication rates at five-year
follow-up. These findings support its viability as a surgical strategy, though long-term
studies are warranted to assess implant durability and survivorship beyond 10 years.
</p>
'The impact of rural infrastructure investment on farmers’ livelihood resilience: Effects and its mechanism' - a #Research article in the Journal of Southern Agriculture on #ScienceOpen:
https://www.scienceopen.com/document?vid=c9b7ece0-bc1c-443e-97fb-8baa7c978bd4
ScienceOpenThe impact of rural infrastructure investment on farmers’ livelihood resilience: Effects and its mechanism<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d11507622e119">
<b>[Objective]</b> To examine the impact of rural infrastructure investment on farmers’ livelihood resilience
and its mechanisms, and to determine whether there was heterogeneity in the effect
of rural infrastructure investment on farmers’ livelihood resilience across different
regions, which could provide decision-making references for advancing rural revitalization
and enhancing farmers’ livelihood resilience.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d11507622e124">
<b>[Method]</b> Based on panel data from 30 provinces in China (excluding Hong Kong, Macau, Taiwan
and Xizang) from 2011 to 2021, this study measured farmers’ livelihood resilience
from 5 aspects: exposure, sensitivity, buffering capacity, learning capacity and self-organization
capacity. Fixed effects model, system GMM model, mediation effect model and threshold
effect model were used to test the impact of rural infrastructure investment on farmers’
livelihood resilience and its mechanisms. The study also explored the mediating roles
of labor transfer, industrial upgrading, and agricultural scale operations in rural
infrastructure investment and farmers’livelihood resilience.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d11507622e129">
<b>[Results]</b> (1) Rural infrastructure investment in the eastern, central, and western regions
of China extremely significantly enhanced farmers’ livelihood resilience (
<i>P</i><0.01, the same below), with the impact coefficient following the pattern: western
region > central region > eastern region, and this effect has strengthened with the
implementation of related policies. (2) In terms of the mechanisms, rural infrastructure
investment promoted farmers’ livelihood resilience by apgrading labor transfer, agricultural
scale operations and industrial structure, with labor transfer being the key pathway.
(3) The regional heterogeneity analysis revealed that the effect of rural infrastructure
investment on farmers’ livelihood resilience was greater in the western and central
regions compared to the eastern region, indicating great regional differences in the
impact of rural infrastructure investment on farmers’ livelihood resilience. (4) As
labor transfer, agricultural scale operations and industrial structure upgraded, the
promotion effect of rural infrastructure investment on farmers’ livelihood resilience
exhibited a nonlinear change. Among these, improving labor transfer and agricultural
scale operations brought significant benefits as complementary measures.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d11507622e137">
<b>[Suggestion]</b> To improve farmers’ livelihood resilience, the following 4 measures should be implemented:
(1) increase investment in rural infrastructure and improve supporting policies; (2)
implement differentiated investment strategies based on local conditions; (3) strengthen
employment security and improve the quality of labor transfer; (4) transform agricultural
production methods to promote agricultural scale development and industrial upgrading.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d11507622e143">
<b>摘要: 【目的】</b> 检验农村基础设施投入对农民生计韧性的影响及其作用机制, 明确不同地区农村基础设施投入对 农民生计韧性的影响是否存在异质性, 为推进乡村全面振兴及提升农民生计韧性提供决策参考。
<b>【方法】</b>基于2011— 2021年我国30个省份 (不含港澳台及西藏) 的平衡面板数据, 从暴露性、敏感性、缓冲能力、学习能力和自组织能力5个 方面对农民生计韧性进行测度,
采用固定效应模型、系统GMM模型、中介效应模型和门槛效应模型, 检验农村基础设 施投入对农民生计韧性的影响及其作用机制, 揭示劳动力转移、产业结构升级和农业规模化经营在农村基础设施投
入与农民生计韧性间的中介作用。
<b>【建议】</b> (1) 我国东部、中部和西部地区的农村基础设施投入均能极显著促进农民生 计韧性 (
<i>P</i><0.01, 下同), 影响系数呈西部>中部>东部的格局, 且随相关政策的实施而提升; (2) 从作用机制分析来看, 农村基础设施投入可通过提升劳动力转移、农业规模化经营和产业结构升级,
而促进农民生计韧性, 尤其劳动力转移 是关键路径; (3) 从区域异质性分析来看, 农村基础设施投入对西部地区和中部地区农民生计韧性的作用效应高于东 部地区, 说明农村基础设施投入对我国不同地区农民生计韧性的影响存在明显差异;
(4) 随着劳动力转移、农业规模 化经营和产业结构升级, 农村基础设施投入对农民生计韧性的推动作用呈非线性变化。其中, 改善劳动力转移和农 业规模化经营水平是带来显著收益的辅助性手段。
<b>【结果】</b>深入认识农村基础设施投入对农民生计韧性的影响, 并从 以下4个方面着手提升农民生计韧性: (1) 提高农村基础设施投入, 完善配套政策; (2) 因地制宜, 实施差异化投入策
略; (3) 加强就业保障, 提升劳动力转移质量; (4) 转变农业生产方式, 推动农业规模化发展和产业结构升级。
</p>
'Diffuse Alveolar Haemorrhage : A Rare but Life-Threatening Pulmonary Complication of Infective Endocarditis' - a new poster published #OpenAccess on #ScienceOpen:
https://www.scienceopen.com/hosted-document?doi=10.14293/P2199-8442.1.SOP-.P0ZQYU.v1
ScienceOpenDIFFUSE ALVEOLAR HAEMORRHAGE : A RARE BUT LIFE-THREATENING PULMONARY COMPLICATION OF INFECTIVE ENDOCARDITIS<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1335651e108"/><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d1335651e109">Infective endocarditis (IE) is a life-threatening condition that may lead to systemic
complications, including diffuse alveolar hemorrhage (DAH), a rare but serious pulmonary
manifestation. We present a case of a 37-year-old male with a history of heavy smoking,
alcohol consumption, and prolonged occupational exposure to cotton dust, who developed
prolonged fever, cough, hemoptysis, and dyspnea. Clinical examination revealed clubbing,
pedal edema, raised JVP, bilateral lung crepitations, and a holosystolic murmur. Blood
cultures confirmed Streptococcus viridans, and echocardiography demonstrated vegetations
consistent with IE. Bronchoalveolar lavage showed sequentially hemorrhagic return
with hemosiderin-laden macrophages, confirming DAH. The patient was managed with intravenous
antibiotics, supportive therapy, and close hemodynamic monitoring. This case highlights
the importance of early recognition and multidisciplinary management of DAH complicating
IE to improve patient outcomes.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d1335651e111"/><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d1335651e112"/>
'Port Infrastructural Investments and Maritime Industry Performance : Evidence From Nigeria' - a new article in the Ibadan Journal of #Sociology by Pluto Journals on #ScienceOpen:
https://www.scienceopen.com/hosted-document?doi=10.13169/ijs.16.1.001
ScienceOpenPORT INFRASTRUCTURAL INVESTMENTS AND MARITIME INDUSTRY PERFORMANCE : EVIDENCE FROM NIGERIA<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1751951e100">This study investigates the relationship between port infrastructural investments
and maritime industry performance in Nigeria. The study aims to evaluate the impact
of port infrastructure investments on maritime industry performance and examine how
vessel turn-around time influences this performance. The research employed Maritime
sector gross domestic product contribution (MSRGDP) as the dependent variable while
Infrastructure index (INFRIN) and Vessel turn-around time (VESTAT) served as the independent
variables. The work used econometric techniques such as ordinary least square (OLS)
regression analysis, and co-integration to study the relationship between the variables
at 5% confidence level. The study using the modified model with an R-Square value
of 0.7224, indicating the model’s goodness of fit, found that investments in port
infrastructure (INFRIN) (with coefficient = 0.3067; p-value = 0.0363) and reductions
in vessel turn-around time (VESTAT) (with coefficient = -0.1642; p-value = 0.0137)
are positively associated with maritime sector GDP (MSRGDP). The results suggest that
in the short term, port infrastructure investments showed an immediate impact on MSRGDP,
while co-integration analysis revealed sustained benefits (p-value = 0.0001 & 0.0245
for trace and maximum eigenvalue respectively) over several years. Also, reduction
in vessel turn-around time revealed an immediate impact on MSRGDP in the short term
and the co-integration analysis depicts endured benefits (p-value = 0.0001 & 0.0475
for trace and maximum eigenvalue) over longer years. The study recommends that the
government should prioritise modernising port facilities, streamlining cargo handling
processes/procedures, and implementing advanced logistics systems to optimise turn-around
time.
</p>
Introducing the Open Press Tilburg University (Open TiU) on #ScienceOpen! 
Discover #OpenAccess #Research across the humanities, law, technology and beyond in three new journal collections, two additional titles coming soon.
Learn more in today's blog post: https://blog.scienceopen.com/2025/06/open-press-tilburg-university-joins-scienceopen/
ScienceOpen Blog · Open Press Tilburg University Joins ScienceOpen - ScienceOpen BlogIntroducing the Open Press Tilburg University (Open TiU) on ScienceOpen! Discover research across the humanities, law, technology and beyond.
'Successful treatment of ultra-high-risk refractory #MultipleMyeloma with anti-BCMA CAR-T therapy followed by allogeneic hematopoietic stem cell transplantation: a case report' - in '#Hematology and #Oncology Discovery' on #ScienceOpen: https://www.scienceopen.com/hosted-document?doi=10.15212/HOD-2023-0003
ScienceOpenSuccessful treatment of ultra-high-risk refractory multiple myeloma with anti-BCMA CAR-T therapy followed by allogeneic hematopoietic stem cell transplantation: a case report<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d7407018e185">Recently, chimeric antigen receptor T cell (CAR-T) therapy targeting B cell maturation
antigen (BCMA) has produced unprecedented and encouraging results in relapsed and/or
refractory multiple myeloma (RRMM) after multiple lines of treatment, especially among
high-risk patients; however, most patients inevitably relapse after CAR-T therapy.
Exploring therapeutic strategies followed by CAR-T therapy has attracted increasing
attention that warrants continued investigation. Herein, we present a young patient
with RRMM and ultra-high-risk genetic abnormalities and refractoriness to a proteasome
inhibitor (bortezomib), immunomodulatory drugs (lenalidomide and pomalidomide), a
cytotoxic drug (liposomal doxorubicin), and anti-CD38 monoclonal antibody. After three
lines of treatment, the patient underwent CAR-T therapy targeting BCMA for salvage
treatment, then achieved a very good partial response with good tolerability. Subsequently,
we performed an allogeneic hematopoietic stem cell transplantation (allo-HSCT) from
an HLA-matched unrelated donor as consolidation therapy. The efficacy was evaluated
as a stringent complete response 42 days after the allo-HSCT. The patient has achieved
progression-free survival for > 9 months after transplantation. The success of our
case demonstrated that for carefully selected patients, anti-BCMA CAR-T therapy followed
by allo-HSCT is effective and feasible in treating RRMM. A longer duration of follow-up
and additional studies are needed to affirm this therapeutic strategy.
</p>
'Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with Echinococcus multilocularis' - a #Research article in the Chinese Journal of #Schistosomiasis Control on #ScienceOpen: https://www.scienceopen.com/document?vid=70b368f5-8810-4e57-8707-0feb6546725d
ScienceOpenProportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with <i>Echinococcus multilocularis</i><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d8563416e215">
<b>Objective</b> To investigate the effects of
<i>Echinococcus multilocularis</i> infection on levels of memory T (Tm) cells and their subsets in lymph nodes of mice
at different stages of infection, so as to provide new insights into immunotherapy
for alveolarechinococcosis.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d8563416e223">
<b>Methods</b> Twenty-four C57BL/6J mice aged 6 to 9 weeks were randomly divided into the infection
group and the control group, of 12 mice in each group. Mice in the infection group
were administered with 3 000
<i>E. multilocularis</i> protoscoleces via portal venous injection, while animals in the control group were
administered with an equal volume of physiological saline. Three mice from each group
were sacrificed 4, 12 weeks and 24 weeks post-infection, and lymph nodes were sampled
and stained with hematoxylin and eosin (HE) to investigate the histopathological changes
of mouse lymph nodes in the infection group. The expression and localization of T
lymphocyte surface markers CD3, CD4, and CD8 were observed in mouse lymph nodes using
immunohistochemical staining. In addition, lymphocyte suspensions were prepared from
mouse lymph nodes in both groups at different time points post-infection, and the
levels of Tm cell subsets and their secreted cytokines were detected using flow cytometry.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d8563416e231">
<b>Results</b> HE staining showed diffuse structural alterations in the subcapsular cortical and
paracortical regions of mouse lymph nodes in the infection group 4 weeks post-infection
with
<i>E. multilocularis</i>. Immunohistochemical staining detected CD3, CD4 and CD8 expression in mouse lymph
nodes in both groups. Flow cytometry revealed higher proportions of CD4
<sup>+</sup> Tm cells [(55.3 ± 4.8)% vs. (38.8 ± 6.1)%;
<i>t</i> = -4.259,
<i>P</i> < 0.05] and CD4
<sup>+</sup> tissue-resident Tm (Trm) cells [(57.7 ± 3.7)% vs. (34.1 ± 11.2)%;
<i>t</i> = -3.990,
<i>P</i> < 0.05] in mouse lymph nodes in the infection group than in the control group 4 weeks
post-infection, and higher proportions of CD4
<sup>+</sup> Tm cells [(34.6 ± 3.2)% vs. (23.3 ± 7.5)%;
<i>t</i> = -2.764,
<i>P</i> < 0.05] and CD4
<sup>+</sup> Trm cells [(44.0 ± 1.9)% vs. (31.2 ± 1.5)%;
<i>t</i> = -4.039,
<i>P</i> < 0.05] in mouse lymph nodes in the infection group than in the control group 24
weeks post-infection. The proportions of CD8
<sup>+</sup> Tm cells were higher in the infection group than in the control group 4 weeks [(56.8
± 2.7)% vs. (43.9 ± 5.2)%;
<i>t</i> = -4.416,
<i>P</i> < 0.01] and 12 weeks post-infection [(25.4 ± 2.7)% vs. (12.0 ± 2.6)%;
<i>t</i> = -2.552,
<i>P</i> < 0.05], while the proportions of tumor necrosis factor (TNF)-α
<sup>+</sup> CD4
<sup>+</sup> T cells [(15.7 ± 5.0)% vs. (49.4 ± 6.4)%;
<i>t</i> = 7.150,
<i>P</i> < 0.01], TNF-α
<sup>+</sup>CD8
<sup>+</sup> T cells [(20.7 ± 5.5)% vs. (57.5 ± 8.4)%;
<i>t</i> = -6.694,
<i>P</i> < 0.01], and TNF-α
<sup>+</sup> CD8
<sup>+</sup> Tm cells [7.0% (1.0%) vs. 31.0% (11.0%);
<i>Z</i> = -2.236,
<i>P</i> < 0.05] were lower in the infection group than in the control group 24 weeks post-infection.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d8563416e331">
<b>Conclusions</b> Tm cells levels are consistently increased in lymph nodes of mice at different stages
of
<i>E. multilocularis</i> infection, with Trm cells as the predominantly elevated subset. The impaired capacity
of CD8
<sup>+</sup> Tm cells to secrete the effector molecule TNF-α in mouse lymph nodes at the late-stage
infection may facilitate chronic parasitism of
<i>E. multilocularis</i>.
</p><p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d8563416e346">
<b>［摘要］ 目的</b>探讨不同阶段多房棘球蚴感染对小鼠淋巴结记忆性T (memory T, Tm) 细胞及其亚群表达水平的影响, 为多房棘球蚴病免疫治疗提供新思路。
<b>方法</b>24只6 ~ 9周龄C57BL/6J小鼠随机分成感染组和对照组, 每组12只; 感染组小鼠经肝门静脉注射3 000 个原头节, 对照组小鼠注射相同体积生理盐水。于感染后第4、12、24周,
每组小鼠分别各随机取3只处死, 取淋巴结组织后采用苏木精-伊红 (hematoxylin and eosin, HE) 染色法观察感染组小鼠淋巴结组织病理变化。通过免疫组织化学染色观察小鼠淋巴结组织中T淋巴细胞表面标志物CD3、CD4和CD8分子表达及定位。提取不同感染时间两组小鼠淋巴结淋巴细胞悬液,
采用流式细胞术检测Tm细胞亚型及其分泌的细胞因子水平。
<b>结果</b>多房棘球蚴感染后4 周, HE染色显示感染组小鼠淋巴结被膜下的皮质和副皮质区域结构呈弥漫性改变。免疫组织化学染色结果显示, 感染组和对照组小鼠淋巴结组织中均有CD3、CD4和CD8分子表达。流式细胞术检测结果显示,
感染后4周, 感染组小鼠淋巴结中CD4
<sup>+</sup> Tm［ (55.3 ± 4.8) % vs. (38.8 ± 6.1) %;
<i>t</i> = -4.259,
<i>P</i> < 0.05］、CD4
<sup>+</sup> 组织驻留记忆性T (tissue-resident memory T, Trm) 细胞比例［ (57.7 ± 3.7) % vs. (34.1 ± 11.2) %;
<i>t</i> = -3.990,
<i>P</i> < 0.05］均显著高于对照组; 感染后24周, 感染组小鼠淋巴结中CD4
<sup>+</sup> Tm［ (34.6 ± 3.2) % vs. (23.3 ± 7.5) %;
<i>t</i> = -2.764,
<i>P</i> < 0.05］、CD4
<sup>+</sup> Trm细胞比例［ (44.0 ± 1.9) % vs. (31.2 ± 1.5) %;
<i>t</i> = -4.039,
<i>P</i> < 0.05］亦显著高于对照组。感染后4 周［ (56.8 ± 2.7) % vs. (43.9 ± 5.2) %;
<i>t</i> = -4.416,
<i>P</i> < 0.01］和12 周［ (25.4 ± 2.7) % vs. (12.0 ± 2.6) %;
<i>t</i> = -2.552,
<i>P</i> < 0.05］, 感染组小鼠淋巴结中CD8
<sup>+</sup> Tm细胞比例均显著高于对照组; 感染后24 周, 感染组小鼠淋巴结中肿瘤坏死因子 (tumor necrosis factor, TNF) -α
<sup>+</sup> CD4
<sup>+</sup> T［ (15.7 ± 5.0) % vs. (49.4 ± 6.4) %;
<i>t</i> = 7.150,
<i>P</i> < 0.01］、TNF-α
<sup>+</sup> CD8
<sup>+</sup> T细胞比例［ (20.7 ± 5.5) % vs. (57.5 ± 8.4) %;
<i>t</i> = -6.694,
<i>P</i> < 0.01］和TNF-α
<sup>+</sup>CD8
<sup>+</sup> Tm细胞比例［7.0% (1.0%) vs. 31.0% (11.0%);
<i>Z</i> = -2.236,
<i>P</i> < 0.05］均显著低于对照组。
<b>结论</b>多房棘球蚴感染不同阶段小鼠淋巴结组织中Tm细胞均增加, 以Trm细胞增加为主; 晚期感染阶段, 小鼠淋巴结组织中CD8
<sup>+</sup> Tm细胞分泌效应分子TNF-α能力减弱, 可能有助于多房棘球蚴慢性寄生。
</p>